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Umbilical cord blood cells restore feeling in paraplegic
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            Sep 29, 2005 13:58 IST  
Reety Arora, 24x7 Updates

In an exceptional breakthrough, Korean scientists helped improve and transform a life by restoring feeling and mobility to a woman suffering from spinal cord injury for about 19 years.

In an exceptional breakthrough, Korean scientists helped improve and transform a life by restoring feeling and mobility to a woman suffering from spinal cord injury for about 19 years. The research, published in the peer-reviewed journal Cythotherapy, has been creating ripples ever since.
These stunning results were reported after the patient was infused with umbilical cord blood cells :

[t]he patient could move her hips and feel her hip skin on day 15 after transplantation. On day 25 after transplantation her feet responded to stimulation. On post operative day (POD) 7, motor activity was noticed and improved gradually in her lumbar paravertebral and hip muscles. She could maintain an upright position by herself on POD 13. From POD 15 she began to elevate both lower legs about 1 cm, and hip flexor muscle activity gradually improved until POD 41.

The bottom line is this, from the Abstract: Not only did the patient regain feeling, but "41 days after [stem cell] transplantation" testing "also showed regeneration of the spinal cord at the injured cite" and below it. "Therefore, it is suggested that Umbilical cord blood multipotent stem cell transplantation could be a good treatment method for Spinal injury patients."

In other words, she regained feeling and some mobility after being paraplegic (complete paraplegia of the 10th thoracic vertebra) for 19 years.

Umbilical cord cells are considered "adult stem cells," in contrast to embryonic stem cells. This relieves many of the raised ethical concerns against the use of embryonic stem cells for whose harvestation a human embryo must be destroyed. Bioethics specialist Wesley J. Smith, writing in Lifesite.com, expressed enthusiasm about the apparent breakthrough, but also urged caution. As one patient does not a treatment make.

Even though this amelioration is credited to the work of the umbilical stem cells scientists did note that the lamenectomy the patient received might have offered some benefit. However the scientists do conclude the transplantation "could be a good treatment method" for paraplegic patients.
The dramatic effect of the story is only added because of the injury being an old one. Yet like most breakthroughs using adult stem cells, this one has been completely ignored by the mainstream media as it supports the positive side of the stem- cell debate. This is just one of those astounding stories that offer tremendous hope for paralyzed patients and their families. For it is the perplexity of hope that keeps the clock of our lives ticking.


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